Rainman,
SD just got voted the city with the most beautiful people, you can live anywhere! Kidding aside, living in SD is really dependent on how much you can afford per month. Some good areas that are not too high priced are Tierrasanta, Lemon Grove and parts of Carmel Valley. Everything here is measured in distance from the coast, the closer you get the higher priced, but the cooler more comfortable the weather, so depending on where it is make sure the place has AC or not. If you have any particular place in mind feel free to drop me an IM and I can give you some more specific gouge. Best of luck!