Oh Ye Olde Wheelegunne... How can something that looks so wrong feel so right?
I became reacquainted with revolvers when S&W released it's Nightguard series during my '08 deployment, and I decided that I needed to own one in .45ACP. In fact, it was second post-deployment purchase (behind a Big Green Egg), as I had to wait for it to be ordered. The local gun store owners looked at me all cross eyed when I asked them for a quote on one, but I would not be deterred. There are pictures in the first couple pages of the 'My Latest Purchase' thread here, I think.
Revolvers are, in my opinion, comparatively simpler when it comes to dealing with malfunctions, because generally speaking, you can get away with pulling the trigger again until the damn thing goes BANG again. There's also only the double action trigger pull to contend with for a safety, which can be good when dealing with a genuine stressful situation. And alternatively, you can always bash Mr. Shithead in the face with it, provided you have a heavy enough gun. My Nightguard and Performance Center 625 both fit in that category, and both have sights that are easily acquirable. The Nightguard has an XS tritium big dot front/rear groove site setup, which works really well in low/no light. The PC 625 has a gold bead and adjustable rear site, which my eyes track much better than the XS. Neither is what I would call imminently concealable, but the Nightguard does a better job than it's longer barreled sibling. I realize that there are any multitude of different frame sizes and barrel lengths available, though, and I do have a hammerless S&W 642 that I carry when I'm looking for something lightweight and very concealable.
Where the real issue arises, though, is when you bring reloads and the act of reloading into the picture. .45ACP revolvers require either .45 auto rim ammo, or the use of moonclips, and either choice presents a rather bulky item (moonclip or speed loader) to carry in a pocket. I mitigate the bulk when I carry .38 by using Bianchi Speed Strips, which present a flatter item for carry in pockets. That presents the other half of the issue: Reloading. Reloading a revolver is mechanically more complicated and vastly different than doing so with a semiautomatic pistol. That sounds like a plain statement, but it wasn't until I considered shooting USPSA with a revolver that I began to realize how different it was. I'm not bad when it comes to reloading any of my production semiautos in competition. The mechanics of my motions are sound, but I've had to work hard to get them where they are. Even then, there are any number of people who make me look like a turtle with a nervous disorder trying to walk uphill on glass when they execute a reload. To seriously approach the matter of reloading a revolver under stress, I had to completely start from scratch. The motions and fine motor skills are just so different. Using something like a Speed Strip (IF it's an option, caliber wise) can be faster, if you practice, but it's not something that I would have been able to do under stress from the get go.
In the end, though, I do enjoy shooting/carrying the occasional wheelgun, but I use them for specific applications. And this is, after all, just one man's opinion.